The chemistry of Enols and Enolate Anions as Nucleophiles (Alkylation and Condensation Reactions). Organic synthesis (protection and deprotection of functional groups, oxidation, reduction, and organometallic compounds. a brief introduction to retrosynthetic analysis, practical issues in synthesis, and selectivity issues. The bulk of the course will consist of a survey of some important classes of reactions, with particular emphasis on mechanistic understanding and rationale for observed selectivity when appropriate. The strategic use of some reactions in complex molecule synthesis will be highlighted.
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