This course contains the scientific basis of human nutrition, digestion, metabolism, and excretion applied to case examples, concepts of illness prevention and disease management, in the context of the individual and society.This course is arranged in 9 PBL cases (a case per week, with 1 week study break after 3rd case, 6th case, and 9th case). Cases are designed in an integrated way around specific case intended learning outcomes (ILOs) which details the learning required around the case topic. The cases contextualize learning to prepare students for the way that doctors meet patient problems. Each case provides the specific context of learning for the week ILOs through which the students should work in the PBL sessions to explore the key concepts they need to cover. These key concepts involve biomedical, behavioral, social, ethical, legal, and professional issues coupled to the theme of the week. The approach to learning around cases will develop students’ skills in collaborative group working and in independent learning. Concomitant to PBL tutorials, lectures and practical sessions will be provided to cover some key learning topics. Additionally, early clinical experience sessions, in which consultation skills (including communication skills) are practiced in small groups will run each week. Students will have the chance for 2 field (hospital and primary care centers) visits during the course to link their learning to practice in real environment and to meet patients.