Course Title: Clinical biochemistry (1) Course Code: CLS 353 Program: Clinical Laboratory Sciences Department: Clinical Laboratory Sciences College: Applied Medical Sciences Institution: Taibah University Version: 2 Last Revision Date: 1/1/1438 AH A. General information about the course: 1. Course Identification 1. Credit hours: (3) (2 T + 1 P) 2. Course type A. ?University ?College ? Department ?Track ?Others B. ? Required ?Elective 3. Level/year at which this course is offered: (level 5/year 3) 4. Course general Description: By the end of this course, the students have to improve his knowledge about the diabetes mellitus and abnormalities correlates, lipoproteins, enzymes, tumor markers, electrolytes, and acid-base balance or imbalance. The student should be able to use the equipment in the laboratory to get accurate results enable him easily to interpret the results of the parameters in the clinical chemistry laboratory. 5. Pre-requirements for this course (if any): Medical biochemistry (2) CLS 244 6. Co-requisites for this course (if any): NA 7. Course Main Objective(s): Upon successful completion of this course, the student should be able to: 1. Discuss abnormal blood glucose levels and diabetes complications. 2. State the classification of, plasma protein, enzymes, electrolytes, and tumor markers. 3. Use the different principles and techniques for testing of analytes. 4. Arrange the lipoprotein classes, function, and relation to disorders. 5. Predict the laboratory findings related to enzymes and hormonal disorders. 6. Discuss the normal and abnormal blood homeostasis. 2. Teaching mode (mark all that apply) No Mode of Instruction Contact Hours Percentage 1 Traditional classroom 60 100% 2 E-learning 3 Hybrid • Traditional classroom • E-learning 4 Distance learning 3. Contact Hours(based on the academic semester) No Activity Contact Hours 96. Lectures 30 97. Laboratory/Studio 30 98. Field 99. Tutorial 100. Others (specify) Total 60 B. Course Learning Outcomes (CLOs), Teaching Strategies and Assessment Methods Code Course Learning Outcomes Code of CLOs aligned with program Teaching Strategies Assessment Methods 1.0 Knowledge and understanding 1.1 Describe the basic information clinical biochemistry field. K1 • Lectures are designed to develop the directions for extra reading by the students on the topics. • Guiding students to using Theoretical exams would contain: • Objective questions (Factual recall, illustrative and/or extended 1.2 Develop theoretical information and critical thinking for interpretation of laboratory results. K Code Course Learning Outcomes Code of CLOs aligned with program Teaching Strategies Assessment Methods references to extract information's. • Discussion of the previous topic. • Interpret of the lecture's outcome every week. • Report and comment on cases study. MCQs & fill in blanks). • Short essay questions • Long essay questions 2.0 Skills 2.1 Apply the operation of automated equipment in the clinical chemistry Laboratory. S1 • Discussions during formal lectures and /or seminars. • Discuss the theory pre and post the practical work. • interpret the findings of laboratory investigations Follow up within the practical sessions: • Objective Structured Practical Examination (OSPE). • Problem solving questions 2.2 Interpret theoretical information for interpretation of laboratory results. S2 2.3 Correlate laboratory parameters to assess both chronic and acute disorders, and predict findings relevant to renal, liver, cardiac, gastrointestinal, and endocrine systems S3 3.0 Values, autonomy, and responsibility 3.1 Generate teamwork activities, sharing of personal ideas, and V1 • Group discussion in • Instructor evaluation and support Code Course Learning Outcomes Code of CLOs aligned with program Teaching Strategies Assessment Methods making group discussion. theory and practical. • Group and individual internet search and analysis for selected topics • Class discussions. activity participation in lectures and practical. • Regularly reports. • Assignments and Homework. C. Course Content No List of Topics Contact Hours 23. Abnormal blood glucose levels 4 2. Diabetes Mellitus (DM) and complications 4 3. Laboratory tests and diagnosis of Diabetes Mellitus 4 4. Plasma proteins 4 5. Protein electrophoresis 4 6. Plasma Lipoproteins 4 7. Lipoproteins disease correlations, and lab test 4 8. Introduction to Clinical Enzymology 4 9. Liver & phosphate enzymes 4 10. Cardiac & pancreatic enzymes 4 11. Enzymes profiles 4 12. Tumor markers 4 13. Electrolytes 4 14. Blood gases, pH, and buffer systems 4 15. Acid-base disorders 4 Total 60 D. Students Assessment Activities No Assessment Activities * Assessment timing (in week no) Percentage of Total Assessment Score 61. Continuous assessment All around semester 5% 62. Midterm examination (written) Week 8-9 15% 63. Assignment submission Week 12 5% 64. Lab report Week 14 5% 5. Practical exam Week 15-16 30% 6. Final written examination Week 17-18 40% *Assessment Activities (i.e., Written test, oral test, oral presentation, group project, essay, etc.). E. Learning Resources and Facilities 1. References and Learning Resources Essential References 1. Michael L. Bishop et.al.(2014) Clinical chemistry principles, procedures, correlations. Lippincott. 2. Marshal WJ.(1997). Clinical chemistry; 3rd edition. Mosby. 3. Varley H.(2002). Practical clinical biochemistry; 4th edition. Arnold. Supportive References 1. Clinical Biochemistry (1st ed.). (2016). Charles University. 2. Carl A. Burtis; Edward R. Ashwood. (2015) Tietz fundamentals of clinical chemistry. 4th edition. Saunders. Electronic Materials 1. Youtube. https://www.youtube.com/ 2. Google images. https://www.google.com.sa/ 3. Taibah University Library e-Book database. https://www.taibahu.edu.sa/Pages/AR/Sector/SectorPage.aspx ?ID=47 4. Learn science at Nature (scitabe) http://www.nature.com/scitable 5. http://www.clinchem.org/ Other Learning Materials 1. Selected films/video clips. 2. Journal of clinical chemistry. 3. Internet resources/ 2. Required Facilities and equipment Items Resources facilities (Classrooms, laboratories, exhibition rooms, simulation rooms, etc.) Lecture room. Chemistry lab. Technology equipment (projector, smart board, software) Data show. Laptop. Internet accessibility. Other equipment (depending on the nature of the specialty) Spectrophotometer - Water bath - Pipettes - (yellow & blue tips) - Vortex - Sensitive balance - Protein electrophoresis (with full facilities) - Flame photometry - ELISA - Blood gas analyzer - Centrifuge - Reagents - Eppendorf tubes - Gloves - Gauze – Tissue papers. F. Assessment of Course Quality Assessment Areas/Issues Assessor Assessment Methods Effectiveness of teaching Instructor ü Direct Method (Rubrics) ü Indirect Method (Questionnaire on the course by the end of the semester) Effectiveness of Students' assessment Head of the department Student achievement is verified by the head of the department. Quality of Learning resources Instructor Student ü Course Report. ü Course Evaluation Survey (CES) Achievement of Course Learning Outcomes Instructor Students ü Direct Method (Rubrics) ü Indirect Method (Questionnaire on the course by the end of the semester) ü Course Evaluation Survey (CES) Effectiveness of Assessment Results Instructor ü Course Report ü Grade Report Analysis ü Course Evaluation Survey (Indirect) Assessors(Students, Faculty, Program Leaders, Peer Reviewer, Others (specify) Assessment Methods(Direct, Indirect)