Course Title: Basic Immunology Course Code: CLS 237 Program: Clinical Laboratory Sciences Department: Clinical Laboratory Sciences College: Applied Medical Sciences Institution: Taibah University Version: 1 Last Revision Date: N/A A. General information about the course: 1. Course Identification 1. Credit hours: (2 CH) 2 T 2. Course type A. ? University ? College ? Department ? Track ? Others B. ? Required ? Elective 3. Level/year at which this course is offered: 3rd level / 2nd year 4. Course general Description: The primary aim of this course is to equip students with a solid understanding of fundamental immunology processes and the intricate interactions within the immune system. It begins by defining the vital role the immune system plays in protecting the body and delves into the basic biology of both innate and adaptive immunity. The course will provide students with in-depth knowledge of the diverse players in the immune system, including cells, tissues, and soluble molecules. It will also explore the fundamental principles of antigen-antibody interactions, unveiling the fascinating dance of recognition and attack. Further exploration will take us to the critical roles of mucosal immunity and immunological memory, while examining the factors influencing immune tolerance. 5. Pre-requirements for this course (if any): None 6. Co-requisites for this course (if any): None 7. Course Main Objective(s): • Distinguish the roles and interactions of various cells and molecules within the immune system. • Detail the first-line defense mechanisms of the innate immune system against pathogens. • Outline the maturation process and activation of B and T lymphocytes in adaptive immunity. • Summarize how antigens are processed and presented to lymphocytes. • Clarify the structure-function relationship of antibodies and their diversity generation. • Evaluate the interactions between T cells and other immune cells in orchestrating immune responses. 2. Teaching mode (mark all that apply) No Mode of Instruction Contact Hours Percentage 1 Traditional classroom 30 100% 2 E-learning 0 0 3 Hybrid • Traditional classroom • E-learning 0 0 4 Distance learning 0 0 3. Contact Hours(based on the academic semester) No Activity Contact Hours 46. Lectures 30 47. Laboratory/Studio 0 48. Field 0 49. Tutorial 0 50. Others (specify) 0 Total 30 B. Course Learning Outcomes (CLOs), Teaching Strategies and Assessment Methods Co de Course Learning Outcomes Prog PLO Teaching Strategies Assessment Methods 1.0 Knowledge and understanding 1.1 Define immunological terminology, clearly distinguishing between innate and adaptive immunity as well as humoral and cell-mediated immune responses. K1 1. Interactive Lectures (intended to provide a solid foundation of knowledge on each topic while also stimulating students' curiosity for additional reading and exploration). 2. Group discussion (Faculty will encourage questions, discussion, and critical thinking during each lecture) • Final exam: (Section 2: Short answer questions) 1.2 Describe the roles and mechanisms of cells, tissues and soluble molecules and receptors in the immune system, including the distinctions and interplay between them. K1 • Final exam: (Section 1: MCQ) 1.3 Describe the different antibody isotypes, their unique functions, and the structural and functional aspects of antigens that determine their immunogenicity. K2 • Final exam: (Section 2: Short answer questions) Co de Course Learning Outcomes Prog PLO Teaching Strategies Assessment Methods 1.4 Explain the process of immune tolerance, mucosal immunity and immunological memory. K2 • Final exam: (Section 3: Long answer questions) 2.0 Skills 2.1 Demonstrate an ability to actively seeking out, analyzing, and applying relevant scientific literature to deepen understanding of immunology. S3 Research topic in the immunology field (Encourage students to conduct individual and group-based literature reviews using online resources. This will not only enhance their understanding of the course content but also improve their research and critical analysis skills Assignment (Assessment rubric) 3.0 Values, autonomy, and responsibility 3.1 Demonstrate teamwork and respect for diverse perspectives recognizing the value of differing viewpoints in scientific progress V3 Oral Presentations: (Students will be required to orally discuss their research findings and essays) Presenting the findings in the Assignment (Assessment rubric) C. Course Content No List of Topics Contact Hours 8. Introduction to Immunology 2 9. Cells and Tissues of the Immune System 2 10. Antigens and Antibodies 2 4. The Complement System 2 5. Major Histocompatibility Complex (MHC) 2 6. Antigen Presentation and Processing 2 7. B and T Lymphocytes 2 8. Lymphocyte Receptors 2 9. The Immune Synapse 2 10. Cytokines and Chemokines 2 11. Immune Tolerance 2 12. Mucosal Immunity 2 13. Immunological Memory 2 14. Laboratory Techniques in Immunology 2 15. Revision 2 Total 30 D. Students Assessment Activities *Assessment Activities (i.e., Written test, oral test, oral presentation, group project, essay, etc.). No Assessment Activities * Assessment timing (in week no) Percentage of Total Assessment Score 25. Assignment Week 12 10 % 26. Midterm examination (written) Week 8-9 20 % 27. Continuous Assessments All around course 30 % 28. Final written examination Week 17-18 40% E. Learning Resources and Facilities 1. References and Learning Resources Essential References Lecture Notes: Immunology, 7th Edition, Ian Todd and Gavin Spickett, 2015, Wiley Blackwell Supportive References Essentials of Clinical Immunology, 6th Edition, Helen Chapel, Mansel Haeney, Siraj Misbah and Neil Snowden, 2014, WileyBlackwell Electronic Materials Microbiology and Immunology Online by Richard Hunt et al. - University of South Carolina, 2004 Other Learning Materials NA 2. Required Facilities and equipment Items Resources facilities Classrooms Technology equipment (projector, smart board, software) Projector + Smartboard Other equipment (depending on the nature of the specialty) F. Assessment of Course Quality Assessment Areas/Issues Assessor Assessment Methods Effectiveness of teaching Instructor ü Direct Method (Rubrics) ü Indirect Method (Questionnaire on the course by the end of the semester) Effectiveness of Students' assessment Head of the department Student achievement is verified by the head of the department. Quality of Learning resources Instructor Student ü Course Report. ü Course Evaluation Survey (CES) Achievement of Course Learning Outcomes Instructor Students ü Direct Method (Rubrics) ü Indirect Method (Questionnaire on the course by the end of the semester) ü Course Evaluation Survey (CES) Effectiveness of Assessment Results Instructor ü Course Report ü Grade Report Analysis ü Course Evaluation Survey (Indirect) Assessors(Students, Faculty, Program Leaders, Peer Reviewer, Others (specify) Assessment Methods(Direct, Indirect)